Association of ADAM33 gene S1 and S2 transmembrane domain polymorphisms in COPD from South-Indian population

Association of ADAM33 gene polymorphisms with allergic asthma

Objective(s): Asthma results from the interaction between genetic and environmental factors. ADAM33 gene on chromosome 20p13 is associated with asthma and airway hyperresponsiveness. Materials and Methods: This is a case-control study, where four SNPs S1 (rs3918396), T1 (rs2280091), T2 (rs2280090), V4 (rs2787094) of ADAM33 gene have been assessed in patients with allergic asthma and normal con...

Author's response to reviews Title: Association of ADAM33 gene polymorphisms with COPD in a northeastern Chinese population Authors:

Association of serotonin transporter gene polymorphisms with obsessive-compulsive disorder (OCD) in a south Indian population

BACKGROUND AND OBJECTIVES Serotonin transporter polymorphisms, 5-HTTVNTR and 5-HTTLPR, have been found to be associated with obsessive-compulsive disorder (OCD) and particularly with neurotic characteristics. In the present study we looked for an association between OCD and these polymorphisms in OCD patients and controls of south Indian origin. METHODS 5-HTTVNTR and 5-HTTLPR/rs25531 were gen...

Association of ADAM33 gene polymorphisms with keloid scars in a northeastern Chinese population.

OBJECTIVE To study the association between ADAM33 and keloid scars in the northeastern Chinese population. METHODS A total of 283 keloid scar patients and a control group of 290 healthy volunteers were recruited for this study. Six polymorphic loci (V4, T+1, T2, T1, S2 and Q-1 ) of ADAM33 were selected for genotyping. Genotypes were determined by using the polymerase chain reaction-restrictio...

Association between ADAM33 S2 and V4 polymorphisms and susceptibility to allergic rhinitis: A meta-analysis.

BACKGROUND It has been reported that ADAM33 (a disintegrin and metalloproteinase domain 33) polymorphisms might be associated with susceptibility to allergic rhinitis (AR). OBJECTIVE Owing to mixed and inconclusive results, we conducted a meta-analysis to systematically summarise and clarify the association between ADAM33 S2, V4, T1, T2 and T+1 polymorphisms and AR risk. METHODS/RESULTS A s...